If Nobilis taught me anything, it was that it’s very interesting to see what ends up exploding when you give PCs the ability to make their dreams come true.
Destinium
Various Hells think that Destinium is an overbearing tool of the hated Creator Who first forced demons into their exile. Various Heavens think that Destinium is a foul concoction brewed by the very Adversary himself in order to more easily destroy mankind. Various organizations aware of the supernatural, the metaphysical, parallel dimensions, alternate timelines, the spirit world, the Great Old Ones, primal energies, tears in reality, the collective tangible unconscious, the ongoing manifestation of the Plane of the Dreamers upon this one, or the Just Plain Weird simply ban Destinium on sight. And why does everybody hate it so much? Because it messes up everybody’s plans, very much including the people it infects.